PDB | 7ld4 Human adenosine A1 receptor-Gi2-protein complex bound to its endogenous agonist
Cryo-EM structure of the human adenosine A1 receptor-Gi2-protein complex bound to its endogenous agonist
label Keywords
signaling protein, membrane protein, active-state g protein-coupled receptor, adenosine a1 receptor
event_note Published
03/12/2025
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
ADENOSINE
Original publication
import_contacts Title
Positive allosteric mechanisms of adenosine A 1 receptor-mediated analgesia.
import_contacts Journal
Nature 2021
import_contacts DOI
10.1038/s41586-021-03897-2
person Authors
Miao, Y., Glukhova, A., Valant, C., Panel, N., Thal, D.M., Carlsson, J., Sexton, P.M., O'Sullivan, K., Venugopal, H., May, L.T., Chia, L.Y., Scammells, P., Christie, M.J., Cowie-Kent, I., Draper-Joyce, C.J., White, P.J., Nguyen, A.T.N., Wang, J., Imlach, W.L., Wootten, D., Danev, R., Bhola, R., Bhattarai, A., Christopoulos, A.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Miao, Y., Glukhova, A., Valant, C., Panel, N., Thal, D.M., Carlsson, J., Sexton, P.M., O'Sullivan, K., Venugopal, H., May, L.T., Chia, L.Y., Scammells, P., Christie, M.J., Cowie-Kent, I., Draper-Joyce, C.J., White, P.J., Nguyen, A.T.N., Wang, J., Imlach, W.L., Wootten, D., Danev, R., Bhola, R., Bhattarai, A., Christopoulos, A. , provided free of copyright via the Protein DataBank. View original data or read license terms.
