PDB | 7l2x RTX-bound minimal TRPV1

cryo-EM structure of RTX-bound minimal TRPV1 with NMDG at state c

label Keywords
trp channel, cryo-em, nanodisc, large cation, vanilloid agonist, transport protein
event_note Published
05/29/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
resiniferatoxin, (10R,13S)-16-amino-13-hydroxy-7,13-dioxo-8,12,14-trioxa-13lambda~5~-phosphahexadecan-10-yl hexadecanoate, 1-deoxy-1-(methylamino)-D-allitol

Original publication

import_contacts Title
Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
import_contacts Journal
Cell 2021
import_contacts DOI
10.1016/j.cell.2021.08.012
person Authors
Julius, D., Cheng, Y., Zhang, K.

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