PDB | 7l2u DkTx-bound minimal TRPV1 in open state

cryo-EM structure of DkTx-bound minimal TRPV1 in open state

label Keywords
trp channel, cryo-em, nanodisc, toxin, transport protein
event_note Published
11/20/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
(2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, (11R,14S)-17-amino-14-hydroxy-8,14-dioxo-9,13,15-trioxa-14lambda~5~-phosphaheptadecan-11-yl decanoate, SODIUM ION

Original publication

import_contacts Title
Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
import_contacts Journal
Cell 2021
import_contacts DOI
10.1016/j.cell.2021.08.012
person Authors
Julius, D., Cheng, Y., Zhang, K.

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