PDB | 7l1v Orexin Receptor 2 (OX2R)
Orexin Receptor 2 (OX2R) in Complex with G Protein and Small-Molecule Agonist Compound 1
label Keywords
class a gpcr, orexin receptor 2, ox2r, membrane protein, peptide agonist
event_note Published
10/30/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
4'-methoxy-N,N-dimethyl-3'-{[3-(2-{[2-(2H-1,2,3-triazol-2-yl)benzene-1-carbonyl]amino}ethyl)phenyl]sulfamoyl}[1,1'-biphenyl]-3-carboxamide
Original publication
import_contacts Title
Structures of active-state orexin receptor 2 rationalize peptide and small-molecule agonist recognition and receptor activation.
import_contacts Journal
Nat Commun 2021
import_contacts DOI
10.1038/s41467-021-21087-6
person Authors
Tummala, S., Soisson, S.M., Breslin, M.J., Xiao, L., Rada, V.L., Hollingsworth, S.A., Hollenstein, K., Byrne, N.J., Shipman, J.M., Minnick, C., Kern, J.C., Brooun, A., Strickland, C., Hong, C., McDonald, T.P., Armacost, K.A., O'Brien, J.A., Stachel, S.J., Zamlynny, B., Hall, D.L., Partridge, A.T., Rudd, M.T.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Tummala, S., Soisson, S.M., Breslin, M.J., Xiao, L., Rada, V.L., Hollingsworth, S.A., Hollenstein, K., Byrne, N.J., Shipman, J.M., Minnick, C., Kern, J.C., Brooun, A., Strickland, C., Hong, C., McDonald, T.P., Armacost, K.A., O'Brien, J.A., Stachel, S.J., Zamlynny, B., Hall, D.L., Partridge, A.T., Rudd, M.T. , provided free of copyright via the Protein DataBank. View original data or read license terms.
