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      PDB | 7k4c Cryo-EM structure of human TRPV6 in complex with (4- phenylcyclohexyl)piperazine inhibitor Br-cis-22a

      Cryo-EM structure of human TRPV6 in complex with (4- phenylcyclohexyl)piperazine inhibitor Br-cis-22a

      label Keywords
      trpv6, ion channel, inhibitor, membrane protein, membrane protein-inhibitor complex
      event_note Published
      03/06/2024
      filter_center_focus Method
      ELECTRON MICROSCOPY
      add_circle Ligands
      1-(5-bromopyridin-3-yl)-4-[cis-4-(3-methylphenyl)cyclohexyl]piperazine, CALCIUM ION

      Original publication

      import_contacts Title
      Inactivation-mimicking block of the epithelial calcium channel TRPV6.
      import_contacts Journal
      Sci Adv 2020
      import_contacts DOI
      10.1126/sciadv.abe1508
      person Authors
      Reymond, J.L., Nadezhdin, K.D., Romanin, C., Neuberger, A., Derler, I., Singh, A.K., Gyimesi, G., Hediger, M.A., Sobolevsky, A.I., Bhardwaj, R., Lindinger, S., Cunha, M.R.

      Read article from Sci Adv

      Member of

      copyrightData provided by Research Collaboration for Structural Biology, Reymond, J.L., Nadezhdin, K.D., Romanin, C., Neuberger, A., Derler, I., Singh, A.K., Gyimesi, G., Hediger, M.A., Sobolevsky, A.I., Bhardwaj, R., Lindinger, S., Cunha, M.R. , provided free of copyright via the Protein DataBank. View original data or read license terms.

      Simulations available

      play_circle_outline7k4c_default_dppc

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