PDB | 7k15 Human Leukotriene B4 Receptor 1
Crystal structure of the Human Leukotriene B4 Receptor 1 in Complex with Selective Antagonist MK-D-046
label Keywords
human leukotriene b4 receptor 1, hblt1, blt1, bltr1, ltb4, ltb4r, lt4r1, ltb4r1, mk-d-046, selective antagonist, inflammation, inflammatory disease, type 2 diabetes, g protein-coupled receptor, gpcr, flavodoxin fusion, membrane protein, lcp
event_note Published
10/16/2024
blur_on Resolution
2.88 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
N-(tert-butylsulfonyl)-4-fluoro-2-{(3S,4R)-4-hydroxy-3-[(pyridin-2-yl)methyl]-3,4-dihydro-2H-1-benzopyran-7-yl}benzamide, SODIUM ION, FLAVIN MONONUCLEOTIDE, OLEIC ACID, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, PENTAETHYLENE GLYCOL, NONAETHYLENE GLYCOL, HEXAETHYLENE GLYCOL
Original publication
import_contacts Title
Structural insights on ligand recognition at the human leukotriene B4 receptor 1.
import_contacts Journal
Nat Commun 2021
import_contacts DOI
10.1038/s41467-021-23149-1
person Authors
Presland, J., Spencer, K.B., Siliphaivanh, P., Cherezov, V., Besserer-Offroy, E., Han, G.W., Zamlynny, B.A., Fradera, X., Katritch, V., Sarret, P., Popov, P., Soisson, S.M., Krishnamurthy, H., Sadybekov, A., Michaelian, N.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Presland, J., Spencer, K.B., Siliphaivanh, P., Cherezov, V., Besserer-Offroy, E., Han, G.W., Zamlynny, B.A., Fradera, X., Katritch, V., Sarret, P., Popov, P., Soisson, S.M., Krishnamurthy, H., Sadybekov, A., Michaelian, N. , provided free of copyright via the Protein DataBank. View original data or read license terms.
