PDB | 7fd9 Thermostabilised full length human mGluR5-5M
Thermostabilised full length human mGluR5-5M with orthosteric antagonist, LY341495
label Keywords
g-protein coupled receptors, signal transduction, metabotropic glutamate receptor, inactive state, membrane protein
event_note Published
11/13/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
2-acetamido-2-deoxy-beta-D-glucopyranose, 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine
Original publication
import_contacts Title
Agonists and allosteric modulators promote signaling from different metabotropic glutamate receptor 5 conformations.
import_contacts Journal
Cell Rep 2021
import_contacts DOI
10.1016/j.celrep.2021.109648
person Authors
Goudet, C., Llebaria, A., Hoh, F., Berto, L., Catena, J., Vinothkumar, K.R., Huang, C.Y., Font-Ingles, J., Gomez-Santacana, X., Quast, R.B., Nasrallah, C., Lebon, G., Pin, J.P., Berizzi, A.E., Baneres, J.L., Malhaire, F., Dumazer, A., Briot, J., Cannone, G., Kniazeff, J., Rottier, K.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Goudet, C., Llebaria, A., Hoh, F., Berto, L., Catena, J., Vinothkumar, K.R., Huang, C.Y., Font-Ingles, J., Gomez-Santacana, X., Quast, R.B., Nasrallah, C., Lebon, G., Pin, J.P., Berizzi, A.E., Baneres, J.L., Malhaire, F., Dumazer, A., Briot, J., Cannone, G., Kniazeff, J., Rottier, K. , provided free of copyright via the Protein DataBank. View original data or read license terms.
