PDB | 7fd8 Thermostabilised full length human mGluR5-5M

Thermostabilised full length human mGluR5-5M bound with L-quisqualic acid

label Keywords
g protein coupled receptors, signal transduction, metabotropic glutamate receptor 5 (grm5), membrane protein
event_note Published
10/30/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
2-acetamido-2-deoxy-beta-D-glucopyranose, (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, CHOLESTEROL HEMISUCCINATE

Original publication

import_contacts Title
Agonists and allosteric modulators promote signaling from different metabotropic glutamate receptor 5 conformations.
import_contacts Journal
Cell Rep 2021
import_contacts DOI
10.1016/j.celrep.2021.109648
person Authors
Goudet, C., Llebaria, A., Hoh, F., Berto, L., Catena, J., Vinothkumar, K.R., Huang, C.Y., Font-Ingles, J., Gomez-Santacana, X., Quast, R.B., Nasrallah, C., Lebon, G., Pin, J.P., Berizzi, A.E., Baneres, J.L., Malhaire, F., Dumazer, A., Briot, J., Cannone, G., Kniazeff, J., Rottier, K.

Loading