PDB | 7ew0 Ozanimod -bound Sphingosine-1-phosphate receptor 1
Cryo-EM structure of ozanimod -bound Sphingosine-1-phosphate receptor 1 in complex with Gi protein
label Keywords
homo sapiens, membrane protein
event_note Published
11/20/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
5-[3-[(1~{S})-1-(2-hydroxyethylamino)-2,3-dihydro-1~{H}-inden-4-yl]-1,2,4-oxadiazol-5-yl]-2-propan-2-yloxy-benzenecarbonitrile
Original publication
import_contacts Title
Structures of signaling complexes of lipid receptors S1PR1 and S1PR5 reveal mechanisms of activation and drug recognition.
import_contacts Journal
Cell Res. 2021
import_contacts DOI
10.1038/s41422-021-00566-x
person Authors
Yang, S., Li, Z., Yuan, Y., Yan, W., Shao, Z., Su, Z., Luo, K., Cheng, L., Wu, C., Wang, W., Jia, G., Li, Q.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Yang, S., Li, Z., Yuan, Y., Yan, W., Shao, Z., Su, Z., Luo, K., Cheng, L., Wu, C., Wang, W., Jia, G., Li, Q. , provided free of copyright via the Protein DataBank. View original data or read license terms.
