PDB | 7epz Erastin-bound xCT-4F2hc complex
Overall structure of Erastin-bound xCT-4F2hc complex
label Keywords
membrane protein
event_note Published
10/30/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
2-[(1S)-1-[4-[2-(4-chloranylphenoxy)ethanoyl]piperazin-1-yl]ethyl]-3-(2-ethoxyphenyl)quinazolin-4-one, 1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHATE
Original publication
import_contacts Title
The structure of erastin-bound xCT-4F2hc complex reveals molecular mechanisms underlying erastin-induced ferroptosis.
import_contacts Journal
Cell Res. 2022
import_contacts DOI
10.1038/s41422-022-00642-w
person Authors
Yan, R., Wang, F., Li, Y., Chi, X., Xie, E., Zhou, Q., Zhang, Y., Hou, T., Li, J., Xu, L., Min, J., Hu, X., Stockwell, B.R.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Yan, R., Wang, F., Li, Y., Chi, X., Xie, E., Zhou, Q., Zhang, Y., Hou, T., Li, J., Xu, L., Min, J., Hu, X., Stockwell, B.R. , provided free of copyright via the Protein DataBank. View original data or read license terms.