PDB | 7epz Erastin-bound xCT-4F2hc complex

Overall structure of Erastin-bound xCT-4F2hc complex

label Keywords
membrane protein
event_note Published
10/30/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
2-[(1S)-1-[4-[2-(4-chloranylphenoxy)ethanoyl]piperazin-1-yl]ethyl]-3-(2-ethoxyphenyl)quinazolin-4-one, 1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHATE

Original publication

import_contacts Title
The structure of erastin-bound xCT-4F2hc complex reveals molecular mechanisms underlying erastin-induced ferroptosis.
import_contacts Journal
Cell Res. 2022
import_contacts DOI
10.1038/s41422-022-00642-w
person Authors
Yan, R., Wang, F., Li, Y., Chi, X., Xie, E., Zhou, Q., Zhang, Y., Hou, T., Li, J., Xu, L., Min, J., Hu, X., Stockwell, B.R.

Loading