PDB | 7eo4 Cryo-EM of Sphingosine 1-phosphate receptor 1 / Gi complex bound to BAF312
Cryo-EM of Sphingosine 1-phosphate receptor 1 / Gi complex bound to BAF312
label Keywords
gpcr, membrane protein
event_note Published
11/06/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
1-[[4-[(~{E})-~{N}-[[4-cyclohexyl-3-(trifluoromethyl)phenyl]methoxy]-~{C}-methyl-carbonimidoyl]-2-ethyl-phenyl]methyl]azetidine-3-carboxylic acid
Original publication
import_contacts Title
Structural basis of sphingosine-1-phosphate receptor 1 activation and biased agonism.
import_contacts Journal
Nat.Chem.Biol. 2022
import_contacts DOI
10.1038/s41589-021-00930-3
person Authors
Cai, X.H., He, Y., Kawakami, K., Inoue, A., Kise, R., Xia, R., Huang, Z., Xu, Z., Sun, M.X., Zhang, A., Guo, C., Qian, Y., Ikuta, T.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Cai, X.H., He, Y., Kawakami, K., Inoue, A., Kise, R., Xia, R., Huang, Z., Xu, Z., Sun, M.X., Zhang, A., Guo, C., Qian, Y., Ikuta, T. , provided free of copyright via the Protein DataBank. View original data or read license terms.
