PDB | 7e1w Hybrid respiratory supercomplex consisting of Mycobacterium tuberculosis complexIII and Mycobacterium smegmatis complexIV in the presence of Q203
Cryo-EM structure of hybrid respiratory supercomplex consisting of Mycobacterium tuberculosis complexIII and Mycobacterium smegmatis complexIV in the presence of Q203
label Keywords
mycobacterium smegmatis, mycobacterium tuberculosis, complexiii, complexiv, electron transport, anti-tb drugs, oxidoreductase
event_note Published
10/16/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
COPPER (II) ION, CARDIOLIPIN, PALMITIC ACID, HEME-A, (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (E)-octadec-9-enoate, PROTOPORPHYRIN IX CONTAINING FE, MENAQUINONE-9, 6-chloranyl-2-ethyl-N-[[4-[4-[4-(trifluoromethyloxy)phenyl]piperidin-1-yl]phenyl]methyl]imidazo[1,2-a]pyridine-3-carboxamide, FE2/S2 (INORGANIC) CLUSTER, (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, HEME C
Original publication
import_contacts Title
Structure of Mycobacterium tuberculosis cytochrome bcc in complex with Q203 and TB47, two anti-TB drug candidates.
import_contacts Journal
Elife 2021
import_contacts DOI
10.7554/eLife.69418
person Authors
Zhou, X., Rao, Z., Xu, J., Wang, Q., Chen, H., Lin, J., Ran, T., Lai, Y., Gong, H., Zhang, Y., Li, D., Yang, X., Tang, Y., Wang, W., Guddat, L.W., Zhou, S., Gao, Y.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Zhou, X., Rao, Z., Xu, J., Wang, Q., Chen, H., Lin, J., Ran, T., Lai, Y., Gong, H., Zhang, Y., Li, D., Yang, X., Tang, Y., Wang, W., Guddat, L.W., Zhou, S., Gao, Y. , provided free of copyright via the Protein DataBank. View original data or read license terms.
