PDB | 7e1v Apo hybrid respiratory supercomplex consisting of Mycobacterium tuberculosis complexIII and Mycobacterium smegmatis complexIV

Cryo-EM structure of apo hybrid respiratory supercomplex consisting of Mycobacterium tuberculosis complexIII and Mycobacterium smegmatis complexIV

label Keywords
mycobacterium smegmatis, mycobacterium tuberculosis, complexiii, complexiv, electron transport, anti-tb drugs, oxidoreductase
event_note Published
11/06/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
COPPER (II) ION, CARDIOLIPIN, PALMITIC ACID, HEME-A, (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (E)-octadec-9-enoate, PROTOPORPHYRIN IX CONTAINING FE, MENAQUINONE-9, FE2/S2 (INORGANIC) CLUSTER, (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, HEME C

Original publication

import_contacts Title
Structure of Mycobacterium tuberculosis cytochrome bcc in complex with Q203 and TB47, two anti-TB drug candidates.
import_contacts Journal
Elife 2021
import_contacts DOI
10.7554/eLife.69418
person Authors
Zhou, X., Rao, Z., Xu, J., Wang, Q., Chen, H., Lin, J., Ran, T., Lai, Y., Gong, H., Zhang, Y., Li, D., Yang, X., Tang, Y., Wang, W., Guddat, L.W., Zhou, S., Gao, Y.

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