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      PDB | 7dxg Structure of SAR7334-bound TRPC6 at 2.9 angstrom

      Structure of SAR7334-bound TRPC6 at 2.9 angstrom

      label Keywords
      trpc6, trpc, fsgs, sar7334, channel, membrane protein
      event_note Published
      06/05/2024
      filter_center_focus Method
      ELECTRON MICROSCOPY
      add_circle Ligands
      ZINC ION, CALCIUM ION, CHOLESTEROL HEMISUCCINATE, 4-[[(1R,2R)-2-[(3R)-3-azanylpiperidin-1-yl]-2,3-dihydro-1H-inden-1-yl]oxy]-3-chloranyl-benzenecarbonitrile, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, [(2S)-2-[(E)-octadec-10-enoyl]oxy-3-oxidanyl-propyl] octadec-10-enoate

      Original publication

      import_contacts Title
      Structural mechanism of human TRPC3 and TRPC6 channel regulation by their intracellular calcium-binding sites.
      import_contacts Journal
      Neuron 2022
      import_contacts DOI
      10.1016/j.neuron.2021.12.023
      person Authors
      Kang, Y., Tang, Q., Wei, M., Wu, J.X., Guo, W., Chen, L.

      Read article from Neuron

      Member of

      copyrightData provided by Research Collaboration for Structural Biology, Kang, Y., Tang, Q., Wei, M., Wu, J.X., Guo, W., Chen, L. , provided free of copyright via the Protein DataBank. View original data or read license terms.

      Simulations available

      play_circle_outline7dxg_default_dppc

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