PDB | 7drk Phosphatidylglycerol phosphate synthase

Crystal structure of phosphatidylglycerol phosphate synthase in complex with cytidine diphosphate-diacylglycerol

label Keywords
substrate complex, phospholipid synthase, staphylococcus aureus, transferase., transferase
event_note Published
12/28/2020
blur_on Resolution
3 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
ZINC ION, 5'-O-[(R)-{[(S)-{(2R)-2,3-bis[(9E)-octadec-9-enoyloxy]propoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]cytidine, SN-GLYCEROL-3-PHOSPHATE, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 1,4-BUTANEDIOL, ACETIC ACID

Original publication

import_contacts Title
The phosphatidylglycerol phosphate synthase PgsA utilizes a trifurcated amphipathic cavity for catalysis at the membrane-cytosol interface.
import_contacts Journal
Curr Res Struct Biol 2021
import_contacts DOI
10.1016/j.crstbi.2021.11.005
person Authors
Liu, Z., Yao, H., Li, D., Yang, B.

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