PDB | 7dfp Human dopamine D2 receptor
Human dopamine D2 receptor in complex with spiperone
label Keywords
g-protein coupled receptor, dopamine receptor, spiperone, membrane protein, antipsychotic, schizophrenia
event_note Published
11/06/2024
blur_on Resolution
3.1 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Original publication
import_contacts Title
Structure of the dopamine D 2 receptor in complex with the antipsychotic drug spiperone.
import_contacts Journal
Nat Commun 2020
import_contacts DOI
10.1038/s41467-020-20221-0
person Authors
Nakane, T., Nomura, N., Im, D., Kimura, K.T., Iwata, S., Fujiwara, T., Inoue, A., Shiimura, Y., Mori, C., Nango, E., Tanaka, T., Yamashita, A., Shimamura, T., Kadji, F.M.N., Aoki, J., Yamanaka, Y., Asada, H., Tono, K., Uemura, T.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Nakane, T., Nomura, N., Im, D., Kimura, K.T., Iwata, S., Fujiwara, T., Inoue, A., Shiimura, Y., Mori, C., Nango, E., Tanaka, T., Yamashita, A., Shimamura, T., Kadji, F.M.N., Aoki, J., Yamanaka, Y., Asada, H., Tono, K., Uemura, T. , provided free of copyright via the Protein DataBank. View original data or read license terms.
