PDB | 7da5 Human MCT1 D309N mutant
Cryo-EM structure of the human MCT1 D309N mutant in complex with Basigin-2 in the inward-open conformation.
label Keywords
proton-coupled monocarboxylate transporter, mct1, basigin, azd3965, single particle cryo-em, latate transporter, transport protein
event_note Published
03/27/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
Original publication
import_contacts Title
Structural basis of human monocarboxylate transporter 1 inhibition by anti-cancer drug candidates.
import_contacts Journal
Cell 2021
import_contacts DOI
10.1016/j.cell.2020.11.043
person Authors
Yuan, Y., Zhu, A., Lei, J., Yan, C., Xu, H., Jiang, X., Zhang, S., Wang, N.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Yuan, Y., Zhu, A., Lei, J., Yan, C., Xu, H., Jiang, X., Zhang, S., Wang, N. , provided free of copyright via the Protein DataBank. View original data or read license terms.
