PDB | 7cx2 PGE2-bound EP2-Gs complex

Cryo-EM structure of the PGE2-bound EP2-Gs complex

label Keywords
gpcr, ep2, complex, pge2, membrane protein
event_note Published
11/06/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
(Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]hept-5-enoic acid

Original publication

import_contacts Title
Ligand recognition, unconventional activation, and G protein coupling of the prostaglandin E 2 receptor EP2 subtype.
import_contacts Journal
Sci Adv 2021
import_contacts DOI
10.1126/sciadv.abf1268
person Authors
Guan, Y., Zhang, P.J., Zhang, Y., Qu, C., Sun, J.P., Yang, F., Yan, X., Shen, D.D., Shen, Q., Zhang, H., Zhao, R.J., Chai, R.J., Zhang, C., Zhong, Y.N., Hou, G., Yu, X., Li, Z., Mao, C., Xiao, P., He, J., Guan, Y.F., Tao, X.

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