PDB | 7cfn INT-777-bound GPBAR-Gs complex
Cryo-EM structure of the INT-777-bound GPBAR-Gs complex
label Keywords
gpcr, gpbar, complex, bile acid, membrane protein
event_note Published
11/20/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
(2S,4R)-4-[(3R,5S,6R,7R,8R,9S,10S,12S,13R,14S,17R)-6-ethyl-10,13-dimethyl-3,7,12-tris(oxidanyl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-pentanoic acid, CHOLESTEROL, PALMITIC ACID
Original publication
import_contacts Title
Structural basis of GPBAR activation and bile acid recognition.
import_contacts Journal
Nature 2020
import_contacts DOI
10.1038/s41586-020-2569-1
person Authors
Xie, X., Wu, X., Zhang, L., Guo, L., Guo, S., Huang, S., Zhang, Y., Ma, C., Sun, J.P., Yi, F., Ping, Y., Yang, F., Nan, F., Liang, X., Shen, D.D., Shen, Q., Zhou, J., Lu, R., Luca, V.C., Ming, Q., Zhang, C., Yu, X., Shen, Y., Mao, C., Xiao, P., Lin, J., Jiang, C., Zhang, K.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Xie, X., Wu, X., Zhang, L., Guo, L., Guo, S., Huang, S., Zhang, Y., Ma, C., Sun, J.P., Yi, F., Ping, Y., Yang, F., Nan, F., Liang, X., Shen, D.D., Shen, Q., Zhou, J., Lu, R., Luca, V.C., Ming, Q., Zhang, C., Yu, X., Shen, Y., Mao, C., Xiao, P., Lin, J., Jiang, C., Zhang, K. , provided free of copyright via the Protein DataBank. View original data or read license terms.
