PDB | 7c83 Integral membrane steroid 5-alpha-reductase PbSRD5A
Crystal structure of an integral membrane steroid 5-alpha-reductase PbSRD5A
label Keywords
steroid reductase, nadph, steroid 3-oxo-delta(4) reduction, oxidoreductase
event_note Published
04/03/2024
blur_on Resolution
2 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
Original publication
import_contacts Title
Crystal structure of steroid reductase SRD5A reveals conserved steroid reduction mechanism.
import_contacts Journal
Nat Commun 2021
import_contacts DOI
10.1038/s41467-020-20675-2
person Authors
Ren, R., Li, Z., Chi, P., Wang, F., Deng, D., Li, F., Sun, B., Pang, B., Chiang, Y.C., Zhu, L., Han, Y., Zhuang, Q., Wang, Q., Wang, S., Zhou, Y., Xiao, Q., Lv, W.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Ren, R., Li, Z., Chi, P., Wang, F., Deng, D., Li, F., Sun, B., Pang, B., Chiang, Y.C., Zhu, L., Han, Y., Zhuang, Q., Wang, Q., Wang, S., Zhou, Y., Xiao, Q., Lv, W. , provided free of copyright via the Protein DataBank. View original data or read license terms.
