PDB | 7bym Cryo-EM structure of human KCNQ4 with retigabine
Cryo-EM structure of human KCNQ4 with retigabine
label Keywords
kcnq, channel, calmodulin, pip2, retigabine, membrane protein
event_note Published
03/27/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
[(2R)-1-octadecanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8Z)-icosa-5,8,11,14-tetraenoate, ethyl N-[2-azanyl-4-[(4-fluorophenyl)methylamino]phenyl]carbamate, POTASSIUM ION
Original publication
import_contacts Title
Structural Basis for the Modulation of Human KCNQ4 by Small-Molecule Drugs.
import_contacts Journal
Mol.Cell 2021
import_contacts DOI
10.1016/j.molcel.2020.10.037
person Authors
Yue, Z., Shen, H., Li, T., Wu, K., Zhang, F., Wang, Y.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Yue, Z., Shen, H., Li, T., Wu, K., Zhang, F., Wang, Y. , provided free of copyright via the Protein DataBank. View original data or read license terms.
