PDB | 7bvq Structure of human beta1 adrenergic receptor bound to carazolol

Structure of human beta1 adrenergic receptor bound to carazolol

label Keywords
g protein coupled receptor, membrane protein, signaling protein
event_note Published
10/30/2024
blur_on Resolution
2.5 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
CHOLESTEROL, (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol, SULFATE ION, (2S)-2,3-dihydroxypropyl (7Z)-tetradec-7-enoate, SODIUM ION, CITRIC ACID, TETRAETHYLENE GLYCOL

Original publication

import_contacts Title
Binding pathway determines norepinephrine selectivity for the human beta 1 AR over beta 2 AR.
import_contacts Journal
Cell Res. 2021
import_contacts DOI
10.1038/s41422-020-00424-2
person Authors
Clark, M.J., Hubner, H., Xu, X., Hirata, K., Kaindl, J., Sunahara, R.K., Gmeiner, P., Liu, X., Kobilka, B.K.

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