PDB | 7bvq Structure of human beta1 adrenergic receptor bound to carazolol
Structure of human beta1 adrenergic receptor bound to carazolol
label Keywords
g protein coupled receptor, membrane protein, signaling protein
event_note Published
10/30/2024
blur_on Resolution
2.5 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
CHOLESTEROL, (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol, SULFATE ION, (2S)-2,3-dihydroxypropyl (7Z)-tetradec-7-enoate, SODIUM ION, CITRIC ACID, TETRAETHYLENE GLYCOL
Original publication
import_contacts Title
Binding pathway determines norepinephrine selectivity for the human beta 1 AR over beta 2 AR.
import_contacts Journal
Cell Res. 2021
import_contacts DOI
10.1038/s41422-020-00424-2
person Authors
Clark, M.J., Hubner, H., Xu, X., Hirata, K., Kaindl, J., Sunahara, R.K., Gmeiner, P., Liu, X., Kobilka, B.K.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Clark, M.J., Hubner, H., Xu, X., Hirata, K., Kaindl, J., Sunahara, R.K., Gmeiner, P., Liu, X., Kobilka, B.K. , provided free of copyright via the Protein DataBank. View original data or read license terms.