PDB | 7bvg Mycobacterium smegmatis arabinosyltransferase EmbA-EmbB-AcpM2
Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with di-arabinose.
label Keywords
mycobacterium smegmatis, cell wall synthesis, drug target, ethambutol, arabinosyltransferase, emba, embb, embc, acyl carrier protein, arabinogalactan, lipoarabinomannan, drug resistance, transferase
event_note Published
03/27/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
[(2Z,6E,10E,14Z,18E,22Z,26Z)-3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaenyl] [(2S,3S,4S,5R)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl] hydrogen phosphate, CARDIOLIPIN, CALCIUM ION, PHOSPHATE ION, 4'-PHOSPHOPANTETHEINE
Original publication
import_contacts Title
Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol.
import_contacts Journal
Science 2020
import_contacts DOI
10.1126/science.aba9102
person Authors
Wang, Q., Zhang, L., Zhang, X., Zhang, B., Zhao, Y., Wu, C., Batt, S.M., Wang, Y., Zhao, W., Xu, W., Bi, L., Yang, H., Guddat, L.W., Gurcha, S.S., Zhu, Y., Besra, G.S., Gao, Y., Wu, F., Veerapen, N., Wang, M., Rao, Z., Gao, R., Zhang, Q., Qin, L., Li, J., Wu, L., Yang, X.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Wang, Q., Zhang, L., Zhang, X., Zhang, B., Zhao, Y., Wu, C., Batt, S.M., Wang, Y., Zhao, W., Xu, W., Bi, L., Yang, H., Guddat, L.W., Gurcha, S.S., Zhu, Y., Besra, G.S., Gao, Y., Wu, F., Veerapen, N., Wang, M., Rao, Z., Gao, R., Zhang, Q., Qin, L., Li, J., Wu, L., Yang, X. , provided free of copyright via the Protein DataBank. View original data or read license terms.
