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PDB | 7b3k Dynamic complex between all-D-enantiomeric peptide D3

Dynamic complex between all-D-enantiomeric peptide D3 with L723P mutant of amyloid precursor protein (APP) 672-726 fragment (amyloid beta 1-55)

label Keywords
d3-peptide, all-d-enantiomeric peptide, australian mutation, amyloid-beta, amyloid precursor protein, complex, transmembrane, protein binding
event_note Published
12/01/2020
filter_center_focus Method
SOLUTION NMR
add_circle Ligands

Original publication

import_contacts Title
All - d - Enantiomeric Peptide D3 Designed for Alzheimer's Disease Treatment Dynamically Interacts with Membrane-Bound Amyloid-beta Precursors.
import_contacts Journal
J.Med.Chem. 2021
import_contacts DOI
10.1021/acs.jmedchem.1c00632
person Authors
Gremer, L., Nadezhdin, K.D., Okhrimenko, I.S., Arseniev, A.S., Dencher, N.A., Kornilov, D.A., Volynsky, P.E., Bocharov, E.V., Bocharova, O.V., Kamynina, A.V., Gordeliy, V.I., Zagryadskaya, Y.A., Kuzmichev, P.K., Bolakhrif, N., Urban, A.S., Efremov, R.G., Willbold, D., Muller-Schiffmann, A., Kutzsche, J.

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