PDB | 7b05 TRPC4 in complex with inhibitor GFB-8749
TRPC4 in complex with inhibitor GFB-8749
label Keywords
ion channel, trpc4, inhibitor, complex, membrane protein, transport protein
event_note Published
05/01/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
4-[4-[[4,4-bis(fluoranyl)cyclohexyl]methyl]-3-oxidanylidene-piperazin-1-yl]-5-chloranyl-1~{H}-pyridazin-6-one, CALCIUM ION, (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate
Original publication
import_contacts Title
Structural basis of TRPC4 regulation by calmodulin and pharmacological agents.
import_contacts Journal
Elife 2020
import_contacts DOI
10.7554/eLife.60603
person Authors
Quentin, D., Stabrin, M., Yu-Strzelczyk, J., Sitsel, O., Malojcic, G., Vinayagam, D., Raunser, S., Yu, M., Ledeboer, M.W., Hofnagel, O., Merino, F., Nagel, G.
copyrightData provided by Research Collaboration for Structural Biology, Quentin, D., Stabrin, M., Yu-Strzelczyk, J., Sitsel, O., Malojcic, G., Vinayagam, D., Raunser, S., Yu, M., Ledeboer, M.W., Hofnagel, O., Merino, F., Nagel, G. , provided free of copyright via the Protein DataBank. View original data or read license terms.