PDB | 7awp Structure of the thermostabilized EAAT1 cryst-II mutant
Structure of the thermostabilized EAAT1 cryst-II mutant in complex with rubidium and barium ions and the allosteric inhibitor UCPH101
label Keywords
excitatory amino acid transporter 1, human glutamate transporter, slc1a3, ion-coupling mechanism, transport protein
event_note Published
01/31/2024
blur_on Resolution
3.91 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile, BARIUM ION, RUBIDIUM ION
Original publication
import_contacts Title
The ion-coupling mechanism of human excitatory amino acid transporters.
import_contacts Journal
Embo J. 2022
import_contacts DOI
10.15252/embj.2021108341
person Authors
Assal, R., Dhenin, J., Kumar, A., Chamot-Rooke, J., Legrand, P., Rey, M., Canul-Tec, J.C., Reyes, N.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Assal, R., Dhenin, J., Kumar, A., Chamot-Rooke, J., Legrand, P., Rey, M., Canul-Tec, J.C., Reyes, N. , provided free of copyright via the Protein DataBank. View original data or read license terms.
