PDB | 7a65 Nanodisc reconstituted, drug-free human ABCB1
Nanodisc reconstituted, drug-free human ABCB1 in complex with MRK16 Fab
label Keywords
p-glycoprotein, mdr1, nanodisc, transport protein
event_note Published
10/23/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
CHOLESTEROL
Original publication
import_contacts Title
Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
import_contacts Journal
Proc.Natl.Acad.Sci.USA 2020
import_contacts DOI
10.1073/pnas.2010264117
person Authors
Irobalieva, R.N., Locher, K.P., Alam, A., Nosol, K., Romane, K., Kowal, J., Fujita, N.
copyrightData provided by Research Collaboration for Structural Biology, Irobalieva, R.N., Locher, K.P., Alam, A., Nosol, K., Romane, K., Kowal, J., Fujita, N. , provided free of copyright via the Protein DataBank. View original data or read license terms.