PDB | 6zoh 3-Formylrifamycin SV binding to the access pocket of AcrB-G619P_G621P L and T protomers
3-Formylrifamycin SV binding to the access pocket of AcrB-G619P_G621P L and T protomers
label Keywords
multidrug efflux pump, membrane protein, transport protein
event_note Published
01/31/2024
blur_on Resolution
2.8 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
DODECYL-BETA-D-MALTOSIDE, 1,2-ETHANEDIOL, GLYCEROL, DODECANE, DECYLAMINE-N,N-DIMETHYL-N-OXIDE, (2S,12Z,14E,16S,17S,18R,19R,20R,21S,22R,23S,24E)-8-formyl-5,6,9,17,19-pentahydroxy-23-methoxy-2,4,12,16,18,20,22-heptam ethyl-1,11-dioxo-1,2-dihydro-2,7-(epoxypentadeca[1,11,13]trienoimino)naphtho[2,1-b]furan-21-yl acetate, (2S)-3-hydroxypropane-1,2-diyl didecanoate, PHOSPHATIDYLETHANOLAMINE, DECANE, (2S)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-hydroxypropyl hexadecanoate, HEXANE
Original publication
import_contacts Title
Allosteric drug transport mechanism of multidrug transporter AcrB.
import_contacts Journal
Nat Commun 2021
import_contacts DOI
10.1038/s41467-021-24151-3
person Authors
Herrmann, A., Foong, W.E., Tam, H.K., Oswald, C., Pos, K.M., Zeng, H.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Herrmann, A., Foong, W.E., Tam, H.K., Oswald, C., Pos, K.M., Zeng, H. , provided free of copyright via the Protein DataBank. View original data or read license terms.
