PDB | 6zod Fusidic acid binding to the allosteric deep transmembrane domain binding pocket, TM7/TM8 groove, and TM1/TM2 groove of the fully induced AcrB T protomer

Fusidic acid binding to the allosteric deep transmembrane domain binding pocket, TM7/TM8 groove, and TM1/TM2 groove of the fully induced AcrB T protomer

label Keywords
multidrug efflux pump, membrane protein, transport protein
event_note Published
01/31/2024
blur_on Resolution
2.85 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
DODECYL-BETA-D-MALTOSIDE, 1,2-ETHANEDIOL, GLYCEROL, DECANE, FUSIDIC ACID, TRIETHYLENE GLYCOL, Octadecane, SULFATE ION, PHOSPHATIDYLETHANOLAMINE, DODECANE, HEXANE

Original publication

import_contacts Title
Allosteric drug transport mechanism of multidrug transporter AcrB.
import_contacts Journal
Nat Commun 2021
import_contacts DOI
10.1038/s41467-021-24151-3
person Authors
Herrmann, A., Foong, W.E., Tam, H.K., Oswald, C., Pos, K.M., Zeng, H.

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