PDB | 6zo5 Fusidic acid binding to the TM1/TM2 groove of AcrB-G619P_G621P
Fusidic acid binding to the TM1/TM2 groove of AcrB-G619P_G621P
label Keywords
multidrug efflux pump, membrane protein, transport protein
event_note Published
01/31/2024
blur_on Resolution
2.5 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL, DODECYL-BETA-D-MALTOSIDE, DODECANE, DECANE, GLYCEROL, HEXANE, 1,2-ETHANEDIOL, (2S)-3-hydroxypropane-1,2-diyl didecanoate, FUSIDIC ACID, TETRADECANE, SULFATE ION, (2S)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-hydroxypropyl hexadecanoate, TRIETHYLENE GLYCOL, PHOSPHATIDYLETHANOLAMINE, N-OCTANE
Original publication
import_contacts Title
Allosteric drug transport mechanism of multidrug transporter AcrB.
import_contacts Journal
Nat Commun 2021
import_contacts DOI
10.1038/s41467-021-24151-3
person Authors
Herrmann, A., Foong, W.E., Tam, H.K., Oswald, C., Pos, K.M., Zeng, H.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Herrmann, A., Foong, W.E., Tam, H.K., Oswald, C., Pos, K.M., Zeng, H. , provided free of copyright via the Protein DataBank. View original data or read license terms.
