PDB | 6zfs Bovine cytochrome bc1
Crystal structure of bovine cytochrome bc1 in complex with quinolone inhibitor WDH-1U-4
label Keywords
cytochrome bc1, malaria, electron transport
event_note Published
01/24/2024
blur_on Resolution
3.5 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, PHOSPHATE ION, CARDIOLIPIN, PROTOPORPHYRIN IX CONTAINING FE, DODECYL-BETA-D-MALTOSIDE, TETRAETHYLENE GLYCOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-methyl-3-[4-[[4-(trifluoromethyloxy)phenyl]methyl]phenyl]-3~{H}-quinolin-4-one, HEME C, FE2/S2 (INORGANIC) CLUSTER, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
Original publication
import_contacts Title
Targeting the ubiquinol-reduction (Qi) site of the mitochondrial cytochrome bc1 complex for the development of next generation quinolone antimalarials
import_contacts Journal
To Be Published ?
import_contacts DOI
?
person Authors
Hasnain, S.S., Amporndanai, K., Hong, W.D., Biangini, G.A., Pidathala, C., O'Neill, P.M., Berry, N., Leung, S.C., Antonyuk, S.V., Amewu, R.K.
copyrightData provided by Research Collaboration for Structural Biology, Hasnain, S.S., Amporndanai, K., Hong, W.D., Biangini, G.A., Pidathala, C., O'Neill, P.M., Berry, N., Leung, S.C., Antonyuk, S.V., Amewu, R.K. , provided free of copyright via the Protein DataBank. View original data or read license terms.
