PDB | 6z3t Structure of canine Sec61 inhibited by mycolactone
Structure of canine Sec61 inhibited by mycolactone
label Keywords
sec61; mycolactone; ribosome-translocon complex; translocation inhibitor, membrane protein
event_note Published
05/22/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
[(6~{S},7~{S},9~{Z},12~{R})-12-[(~{Z},2~{S},6~{R},7~{R},9~{R})-4,6-dimethyl-7,9-bis(oxidanyl)dec-4-en-2-yl]-7,9-dimethyl-2-oxidanylidene-1-oxacyclododec-9-en-6-yl] (2~{E},4~{E},6~{E},8~{E},10~{E},12~{S},13~{S},15~{S})-4,6,10-trimethyl-12,13,15-tris(oxidanyl)hexadeca-2,4,6,8,10-pentaenoate
Original publication
import_contacts Title
Structure of the Inhibited State of the Sec Translocon.
import_contacts Journal
Mol.Cell 2020
import_contacts DOI
10.1016/j.molcel.2020.06.013
person Authors
Gerard, S.F., Mayerhofer, P.U., Zaki, A.M., Hall, B.S., Biggin, P.C., Costa, C., Simmonds, R.E., Higgins, M.K., Corfield, K.A., Whelligan, D.K.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Gerard, S.F., Mayerhofer, P.U., Zaki, A.M., Hall, B.S., Biggin, P.C., Costa, C., Simmonds, R.E., Higgins, M.K., Corfield, K.A., Whelligan, D.K. , provided free of copyright via the Protein DataBank. View original data or read license terms.
