PDB | 6xvf Bovine cytochrome bc1
Crystal structure of bovine cytochrome bc1 in complex with tetrahydro-quinolone inhibitor JAG021
label Keywords
cytochrome bc1, malaria, electron transport, membrane protein
event_note Published
01/24/2024
blur_on Resolution
3.5 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
TETRAETHYLENE GLYCOL, 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, PHOSPHATE ION, CARDIOLIPIN, PROTOPORPHYRIN IX CONTAINING FE, DODECYL-BETA-D-MALTOSIDE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-methyl-3-[4-[4-(trifluoromethyloxy)phenoxy]phenyl]-5,6,7,8-tetrahydro-3~{H}-quinolin-4-one, HEME C, FE2/S2 (INORGANIC) CLUSTER, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
Original publication
import_contacts Title
Potent Tetrahydroquinolone Eliminates Apicomplexan Parasites.
import_contacts Journal
Front Cell Infect Microbiol 2020
import_contacts DOI
10.3389/fcimb.2020.00203
person Authors
Moreno, S.N., Antonyuk, S.V., Lee, P.J., Priestley, R.S., Zhou, Y., McPhillie, M.J., Weber, C.R., Johnson, R.M., Sinai, A.P., Li, Q., Hakim, F.E., Gordon, J.A., Dubey, J.P., Prud'homme, R.K., Roberts, L., Cong, H., Darby, H., Roberts, C.W., Woods, S., McLeod, R., Ristroph, K.D., Biagini, G.A., Li, Z.H., Biering, S.B., Dovgin, S.M., Lykins, J.D., Fishwick, C.W.G., Hwang, S., Amporndanai, K., Muench, S.P., El Bissati, K., Hargrave, K., Hickman, M.R., Lorenzi, H.A.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Moreno, S.N., Antonyuk, S.V., Lee, P.J., Priestley, R.S., Zhou, Y., McPhillie, M.J., Weber, C.R., Johnson, R.M., Sinai, A.P., Li, Q., Hakim, F.E., Gordon, J.A., Dubey, J.P., Prud'homme, R.K., Roberts, L., Cong, H., Darby, H., Roberts, C.W., Woods, S., McLeod, R., Ristroph, K.D., Biagini, G.A., Li, Z.H., Biering, S.B., Dovgin, S.M., Lykins, J.D., Fishwick, C.W.G., Hwang, S., Amporndanai, K., Muench, S.P., El Bissati, K., Hargrave, K., Hickman, M.R., Lorenzi, H.A. , provided free of copyright via the Protein DataBank. View original data or read license terms.
