PDB | 6xbm Structure of human SMO-Gi complex

Structure of human SMO-Gi complex with 24(S),25-EC

label Keywords
gpcr, membrane protein
event_note Published
10/09/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
17-[3-(3,3-DIMETHYL-OXIRANYL)-1-METHYL-PROPYL]-10,13-DIMETHYL-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYC LOPENTA[A]PHENANTHREN-3-OL

Original publication

import_contacts Title
Sterols in an intramolecular channel of Smoothened mediate Hedgehog signaling.
import_contacts Journal
Nat.Chem.Biol. 2020
import_contacts DOI
10.1038/s41589-020-0646-2
person Authors
De Bose-Boyd, R., Friedberg, L., Long, T., Qi, X., Li, X.

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