PDB | 6x40 Human GABAA receptor alpha1-beta2-gamma2 subtype
Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus picrotoxin
label Keywords
ion channel, cys-loop receptor, pentametic ligand gated channel, gabaa receptor, membrane protein
event_note Published
10/30/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, (1aR,2aR,3S,6R,6aS,8aS,8bR,9R)-2a-hydroxy-8b-methyl-9-(prop-1-en-2-yl)hexahydro-3,6-methano-1,5,7-trioxacyclopenta[ij]c yclopropa[a]azulene-4,8(3H)-dione
Original publication
import_contacts Title
Shared structural mechanisms of general anaesthetics and benzodiazepines.
import_contacts Journal
Nature 2020
import_contacts DOI
10.1038/s41586-020-2654-5
person Authors
Kim, J.J., Noviello, C.M., Lindahl, E., Howard, R.J., Zhuang, Y., Walsh Jr., R.M., Gharpure, A., Hibbs, R.E., Teng, J., Zhu, S.
copyrightData provided by Research Collaboration for Structural Biology, Kim, J.J., Noviello, C.M., Lindahl, E., Howard, R.J., Zhuang, Y., Walsh Jr., R.M., Gharpure, A., Hibbs, R.E., Teng, J., Zhu, S. , provided free of copyright via the Protein DataBank. View original data or read license terms.
