PDB | 6wv5 Human VKOR C43S mutant
Human VKOR C43S mutant with vitamin K1 epoxide
label Keywords
vitamin k epoxide reductase (vkor), vitamin k, warfarin, superwarfarin, vitamin k expoxide(ko), membrane protein, oxidoreductase, fluorescent protein
event_note Published
10/23/2024
blur_on Resolution
2.8 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
(2R,3R)-2-hydroxy-3-methyl-2-[(2E,7S)-3,7,11,15-tetramethylhexadec-2-en-1-yl]-2,3-dihydronaphthalene-1,4-dione
Original publication
import_contacts Title
Structural basis of antagonizing the vitamin K catalytic cycle for anticoagulation.
import_contacts Journal
Science 2021
import_contacts DOI
10.1126/science.abc5667
person Authors
Liu, S., Krezel, A.M., Shen, G., Li, W., Li, S., Sukumar, N.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Liu, S., Krezel, A.M., Shen, G., Li, W., Li, S., Sukumar, N. , provided free of copyright via the Protein DataBank. View original data or read license terms.
