PDB | 6wbv Structure of human ferroportin bound to hepcidin and cobalt in lipid nanodisc
Structure of human ferroportin bound to hepcidin and cobalt in lipid nanodisc
label Keywords
ferroportin, transporter, iron, hepcidin, translocase-immune system-hormone complex
event_note Published
10/23/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
(1S)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PENTANOYLOXY)METHYL]ETHYL OCTANOATE, COBALT (II) ION
Original publication
import_contacts Title
Structure of hepcidin-bound ferroportin reveals iron homeostatic mechanisms.
import_contacts Journal
Nature 2020
import_contacts DOI
10.1038/s41586-020-2668-z
person Authors
Powers, A.S., Kretsch, R.C., Azumaya, C.M., Cheng, Y., Arvedson, T., Manglik, A., Billesbolle, C.B., Schneider, S., Gonen, S., Dror, R.O.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Powers, A.S., Kretsch, R.C., Azumaya, C.M., Cheng, Y., Arvedson, T., Manglik, A., Billesbolle, C.B., Schneider, S., Gonen, S., Dror, R.O. , provided free of copyright via the Protein DataBank. View original data or read license terms.
