PDB | 6w5s NPC1 structure in GDN micelles at pH 8.0
NPC1 structure in GDN micelles at pH 8.0
label Keywords
cholesterol lysosome, transport protein
event_note Published
11/06/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate
Original publication
import_contacts Title
Structural Basis of Low-pH-Dependent Lysosomal Cholesterol Egress by NPC1 and NPC2.
import_contacts Journal
Cell 2020
import_contacts DOI
10.1016/j.cell.2020.05.020
person Authors
Wu, X., Lee, J., Qian, H., Yang, H., Zhao, X., Yao, X., Du, X., Yan, N.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Wu, X., Lee, J., Qian, H., Yang, H., Zhao, X., Yao, X., Du, X., Yan, N. , provided free of copyright via the Protein DataBank. View original data or read license terms.
