PDB | 6w1y 5HT3A receptor in presence of Palonosetron

Cryo-EM structure of 5HT3A receptor in presence of Palonosetron

label Keywords
transport protein
event_note Published
11/06/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
(3~{a}~{S})-2-[(3~{S})-1-azabicyclo[2.2.2]octan-3-yl]-3~{a},4,5,6-tetrahydro-3~{H}-benzo[de]isoquinolin-1-one

Original publication

import_contacts Title
High-resolution structures of multiple 5-HT 3A R-setron complexes reveal a novel mechanism of competitive inhibition.
import_contacts Journal
Elife 2020
import_contacts DOI
10.7554/eLife.57870
person Authors
Kumar, A., Kapoor, A., Basak, S., Filizola, M., Ramsey, S., Chakrapani, S., Gibbs, E.

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