PDB | 6vm2 Full length Glycine receptor reconstituted in lipid nanodisc in Gly/IVM-conformation (State-2)

Full length Glycine receptor reconstituted in lipid nanodisc in Gly/IVM-conformation (State-2)

label Keywords
ions ligands receptors, glycine receptor recombinant proteins glycine, membrane protein
event_note Published
05/21/2025
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate, GLYCINE, (2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17 -oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacy clooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside

Original publication

import_contacts Title
Mechanisms of activation and desensitization of full-length glycine receptor in lipid nanodiscs.
import_contacts Journal
Nat Commun 2020
import_contacts DOI
10.1038/s41467-020-17364-5
person Authors
Kumar, A., Mayer, M.L., Gicheru, Y., Basak, S., Chakrapani, S., Sansom, M.S.P., Rao, S.

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