PDB | 6vl4 MPGES-1 bound to DG-031
Crystal Structure of mPGES-1 bound to DG-031
label Keywords
mpges-1, membrane protein, isomerase
event_note Published
10/23/2024
blur_on Resolution
1.4 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
(2R)-cyclopentyl{4-[(quinolin-2-yl)methoxy]phenyl}acetic acid, octyl beta-D-glucopyranoside, TETRAETHYLENE GLYCOL
Original publication
import_contacts Title
Structure-based, multi-targeted drug discovery approach to eicosanoid inhibition: Dual inhibitors of mPGES-1 and 5-lipoxygenase activating protein (FLAP).
import_contacts Journal
Biochim Biophys Acta Gen Subj 2020
import_contacts DOI
10.1016/j.bbagen.2020.129800
person Authors
Chandrasekhar, S., Yu, X.P., Rauch, C.T., Kahl, S.D., Aznavour, K., Norman, B.H., Hickey, M.J., Park, J.S., Luz, J.G., Zhang, A., Ho, J.D., Hughes, N.E., Lee, M.R., Gooding, K., Antonysamy, S., Maletic, M., Condon, B., Harvey, A., Sloan, A.V.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Chandrasekhar, S., Yu, X.P., Rauch, C.T., Kahl, S.D., Aznavour, K., Norman, B.H., Hickey, M.J., Park, J.S., Luz, J.G., Zhang, A., Ho, J.D., Hughes, N.E., Lee, M.R., Gooding, K., Antonysamy, S., Maletic, M., Condon, B., Harvey, A., Sloan, A.V. , provided free of copyright via the Protein DataBank. View original data or read license terms.
