PDB | 6vgc Crystal Structures of FLAP bound to DG-031
Crystal Structures of FLAP bound to DG-031
label Keywords
5-lipoxygenase activating protein, flap, dg-031, membrane protein
event_note Published
01/07/2020
blur_on Resolution
2.37 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
(2R)-cyclopentyl{4-[(quinolin-2-yl)methoxy]phenyl}acetic acid, CALCIUM ION, octyl beta-D-glucopyranoside
Original publication
import_contacts Title
Structure-based, multi-targeted drug discovery approach to eicosanoid inhibition: Dual inhibitors of mPGES-1 and 5-lipoxygenase activating protein (FLAP).
import_contacts Journal
Biochim Biophys Acta Gen Subj 2020
import_contacts DOI
10.1016/j.bbagen.2020.129800
person Authors
Chandrasekhar, S., Yu, X.P., Rauch, C.T., Kahl, S.D., Aznavour, K., Norman, B.H., Hickey, M.J., Park, J.S., Luz, J.G., Zhang, A., Ho, J.D., Hughes, N.E., Lee, M.R., Gooding, K., Antonysamy, S., Maletic, M., Condon, B., Harvey, A., Sloan, A.V.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Chandrasekhar, S., Yu, X.P., Rauch, C.T., Kahl, S.D., Aznavour, K., Norman, B.H., Hickey, M.J., Park, J.S., Luz, J.G., Zhang, A., Ho, J.D., Hughes, N.E., Lee, M.R., Gooding, K., Antonysamy, S., Maletic, M., Condon, B., Harvey, A., Sloan, A.V. , provided free of copyright via the Protein DataBank. View original data or read license terms.
