PDB | 6v3f Structure of NPC1-like intracellular cholesterol transporter 1 (NPC1L1)
Structure of NPC1-like intracellular cholesterol transporter 1 (NPC1L1)
label Keywords
cholesterol, transporter, tunnel, sterol, intestine, ezetimibe, sterol-sensing domain, lipid transport
event_note Published
10/23/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL
Original publication
import_contacts Title
Cryo-EM structures of NPC1L1 reveal mechanisms of cholesterol transport and ezetimibe inhibition
import_contacts Journal
Sci Adv 2020
import_contacts DOI
10.1126/sciadv.abb1989
person Authors
Chiu, W., Min, X., Fordstrom, P., Huang, C.S., Wang, Z., Yu, X., Zhou, M., Roh, S.H., Choi, K., Chung, B.C.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Chiu, W., Min, X., Fordstrom, P., Huang, C.S., Wang, Z., Yu, X., Zhou, M., Roh, S.H., Choi, K., Chung, B.C. , provided free of copyright via the Protein DataBank. View original data or read license terms.
