PDB | 6usf Human alpha4beta2 nicotinic acetylcholine receptor
CryoEM structure of human alpha4beta2 nicotinic acetylcholine receptor with varenicline in complex with anti-BRIL synthetic antibody BAK5
label Keywords
acetylcholine receptor, nicotine, varenicline, anti-bril synthetic antibody, membrane protein, membrane protein-immune system complex
event_note Published
11/13/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
2-acetamido-2-deoxy-beta-D-glucopyranose, VARENICLINE, beta-D-mannopyranose
Original publication
import_contacts Title
Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins.
import_contacts Journal
Nat Commun 2020
import_contacts DOI
10.1038/s41467-020-15363-0
person Authors
Yeager, M., Coukos, J., Gao, X., Kang, Y., Radziwon, K., Skrobek, B.M., Purdy, M.D., Alvarez, F.J.D., Eric Xu, H., Dutka, P., Han, S., Ammirati, M., Kossiakoff, A.A., Fennell, K.F., Erramilli, S.K., Mukherjee, S., Qiu, X.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Yeager, M., Coukos, J., Gao, X., Kang, Y., Radziwon, K., Skrobek, B.M., Purdy, M.D., Alvarez, F.J.D., Eric Xu, H., Dutka, P., Han, S., Ammirati, M., Kossiakoff, A.A., Fennell, K.F., Erramilli, S.K., Mukherjee, S., Qiu, X. , provided free of copyright via the Protein DataBank. View original data or read license terms.
