PDB | 6t9n Human polycystin-2/PKD2 in UDM supplemented

CryoEM structure of human polycystin-2/PKD2 in UDM supplemented with PI(4,5)P2

label Keywords
ion channel, transient receptor potential channel, polycystic kidney disease, structural genomics, structural genomics consortium, sgc, membrane protein
event_note Published
10/23/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
CHOLESTEROL, 2-acetamido-2-deoxy-beta-D-glucopyranose, UNDECYL-MALTOSIDE, CALCIUM ION

Original publication

import_contacts Title
Lipid Interactions of a Ciliary Membrane TRP Channel: Simulation and Structural Studies of Polycystin-2.
import_contacts Journal
Structure 2020
import_contacts DOI
10.1016/j.str.2019.11.005
person Authors
Shi, J., Wang, Q., Grieben, M., Sansom, M.S.P., Hedger, G., Nasrallah, C., Carpenter, E.P., Aryal, P., Baronina, A., Corey, R.A., Pike, A.C.W.

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