PDB | 6s8h Cryo-EM structure of LptB2FG in complex with LPS
Cryo-EM structure of LptB2FG in complex with LPS
label Keywords
lipopolysaccharide transporter, lps, lptb2fgc, lptb, lptbfg, outer membrane, gram-negative bacteria, abc transporter, inner membrane protein complex, transport protein
event_note Published
05/22/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
Lauryl Maltose Neopentyl Glycol, (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-5-[(2~{S},3~{S},4~{R},5~{R},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-4-[(2~{R},3~{S},4~{R},5~{S},6~{R})-6-[(1~{S})-2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-1-oxidanyl-ethyl]-3,4-bis(oxidanyl)-5-phosphonooxy-oxan-2-yl]oxy-3-oxidanyl-5-phosphonooxy-oxan-2-yl]oxy-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, DODECYL-BETA-D-MALTOSIDE
Original publication
import_contacts Title
Cryo-EM structures of lipopolysaccharide transporter LptB2FGC in lipopolysaccharide or AMP-PNP-bound states reveal its transport mechanism.
import_contacts Journal
Nat Commun 2019
import_contacts DOI
10.1038/s41467-019-11977-1
person Authors
Dong, H., Qiao, W., Zhu, X., Zhang, Z., Wei, X., Niu, Y., Zhang, C., Luo, Q., Yang, W., Tang, X., Xu, C., Chang, S., Zhang, X., Dong, C., Wang, T.
copyrightData provided by Research Collaboration for Structural Biology, Dong, H., Qiao, W., Zhu, X., Zhang, Z., Wei, X., Niu, Y., Zhang, C., Luo, Q., Yang, W., Tang, X., Xu, C., Chang, S., Zhang, X., Dong, C., Wang, T. , provided free of copyright via the Protein DataBank. View original data or read license terms.
