PDB | 6rz6 Human cysteinyl leukotriene receptor 2
Crystal structure of the human cysteinyl leukotriene receptor 2 in complex with ONO-2570366 (C2221 space group)
label Keywords
gpcr, lcp, membrane protein, cysteinyl leukotriene, cyslt2, cysltr2, cyslt2r, asthma, bril, cysteinyl leukotriene receptor 2
event_note Published
11/06/2024
blur_on Resolution
2.43 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
(2~{S})-8-[[4-[4-(2-chloranyl-5-fluoranyl-phenyl)butoxy]phenyl]carbonylamino]-4-(4-oxidanyl-4-oxidanylidene-butyl)-2,3- dihydro-1,4-benzoxazine-2-carboxylic acid, CHOLESTEROL, L(+)-TARTARIC ACID, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, OLEIC ACID, PENTAETHYLENE GLYCOL
Original publication
import_contacts Title
Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors.
import_contacts Journal
Nat Commun 2019
import_contacts DOI
10.1038/s41467-019-13348-2
person Authors
Brouillette, R.L., Mishin, A., Patel, N., Gordeliy, V., Besserer-Offroy, E., Han, G.W., Ishchenko, A., Longpre, J.M., Shevtsov, M., Stauch, B., Ergasheva, M., Marin, E., Gusach, A., Katritch, V., Fujimoto, T., Maruyama, T., Romanovskaia, D., Popov, P., Cherezov, V., Kovalev, K., Stepko, A., Sarret, P., Luginina, A., Borshchevskiy, V.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Brouillette, R.L., Mishin, A., Patel, N., Gordeliy, V., Besserer-Offroy, E., Han, G.W., Ishchenko, A., Longpre, J.M., Shevtsov, M., Stauch, B., Ergasheva, M., Marin, E., Gusach, A., Katritch, V., Fujimoto, T., Maruyama, T., Romanovskaia, D., Popov, P., Cherezov, V., Kovalev, K., Stepko, A., Sarret, P., Luginina, A., Borshchevskiy, V. , provided free of copyright via the Protein DataBank. View original data or read license terms.
