PDB | 6rz5 Human cysteinyl leukotriene receptor 1
XFEL crystal structure of the human cysteinyl leukotriene receptor 1 in complex with zafirlukast
label Keywords
gpcr, lcp, membrane protein, cysteinyl leukotriene, ltd4, cyslt1, cysltr1, cyslt1r, asthma, zafirlukast, bril, sodium site, cysteinyl leukotriene receptor 1, xfel, serial femtosecond crystallography, sfx
event_note Published
11/13/2024
blur_on Resolution
2.53 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
zafirlukast, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, OLEIC ACID, PENTAETHYLENE GLYCOL, SODIUM ION
Original publication
import_contacts Title
Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs.
import_contacts Journal
Sci Adv 2019
import_contacts DOI
10.1126/sciadv.aax2518
person Authors
Mishin, A., Patel, N., Gordeliy, V., Besserer-Offroy, E., Han, G.W., Safronova, N., Ishchenko, A., Longpre, J.M., Lyapina, E., Hu, H., Marin, E., Gusach, A., Katritch, V., Polovinkin, V., Edelweiss, E., Popov, P., Batyuk, A., Liu, W., Weierstall, U., Cherezov, V., Sarret, P., Brouillette, R., Luginina, A., Bogorodskiy, A., Borshchevskiy, V., Shiriaeva, A.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Mishin, A., Patel, N., Gordeliy, V., Besserer-Offroy, E., Han, G.W., Safronova, N., Ishchenko, A., Longpre, J.M., Lyapina, E., Hu, H., Marin, E., Gusach, A., Katritch, V., Polovinkin, V., Edelweiss, E., Popov, P., Batyuk, A., Liu, W., Weierstall, U., Cherezov, V., Sarret, P., Brouillette, R., Luginina, A., Bogorodskiy, A., Borshchevskiy, V., Shiriaeva, A. , provided free of copyright via the Protein DataBank. View original data or read license terms.
