PDB | 6rz4 Cysteinyl leukotriene receptor 1

Crystal structure of cysteinyl leukotriene receptor 1 in complex with pranlukast

label Keywords
gpcr, lcp, membrane protein, cysteinyl leukotriene, ltd4, cyslt1, cysltr1, cyslt1r asthma, pranlukast, bril, sodium site, cysteinyl leukotriene receptor 1
event_note Published
11/13/2024
blur_on Resolution
2.7 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
pranlukast, SODIUM ION, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, OLEIC ACID

Original publication

import_contacts Title
Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs.
import_contacts Journal
Sci Adv 2019
import_contacts DOI
10.1126/sciadv.aax2518
person Authors
Mishin, A., Patel, N., Gordeliy, V., Besserer-Offroy, E., Han, G.W., Safronova, N., Ishchenko, A., Longpre, J.M., Lyapina, E., Hu, H., Marin, E., Gusach, A., Katritch, V., Polovinkin, V., Edelweiss, E., Popov, P., Batyuk, A., Liu, W., Weierstall, U., Cherezov, V., Sarret, P., Brouillette, R., Luginina, A., Bogorodskiy, A., Borshchevskiy, V., Shiriaeva, A.

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