PDB | 6rv2 Human two pore domain potassium ion channel TASK-1 (K2P3.1) in a closed conformation
Crystal structure of the human two pore domain potassium ion channel TASK-1 (K2P3.1) in a closed conformation
label Keywords
membrane protein, potassium channel, structural genomics, structural genomics consortium, sgc
event_note Published
01/24/2024
blur_on Resolution
3 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
POTASSIUM ION, CHOLESTEROL HEMISUCCINATE, DECYL-BETA-D-MALTOPYRANOSIDE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE
Original publication
import_contacts Title
A lower X-gate in TASK channels traps inhibitors within the vestibule.
import_contacts Journal
Nature 2020
import_contacts DOI
10.1038/s41586-020-2250-8
person Authors
Zhang, W., Rodstrom, K.E.J., Pike, A.C.W., Decher, N., Burgess-Brown, N.A., Mukhopadhyay, S.M.M., Muller, T., Hahn, M.G., Delbeck, M., Tucker, S.J., Speedman, D., Shrestha, L., Quigley, A., Meier, H., Carpenter, E.P., Kiper, A.K., Rinne, S., Conrad, L.J., Goldstein, M., Platzk, M.
copyrightData provided by Research Collaboration for Structural Biology, Zhang, W., Rodstrom, K.E.J., Pike, A.C.W., Decher, N., Burgess-Brown, N.A., Mukhopadhyay, S.M.M., Muller, T., Hahn, M.G., Delbeck, M., Tucker, S.J., Speedman, D., Shrestha, L., Quigley, A., Meier, H., Carpenter, E.P., Kiper, A.K., Rinne, S., Conrad, L.J., Goldstein, M., Platzk, M. , provided free of copyright via the Protein DataBank. View original data or read license terms.
